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Experiments and Observations on the Gastric Juice and the Physiology of Digestion.
Plattsburgh: F.P. Allen, 1833. First edition. Period (presumably publisher's) boards backed with salmon cloth spine retaining fragments of the lettering-piece, housed in a modern cloth slipcase. 8 3/4 x 5 3/8 inches (22 x 13.75 cm); 280 pp., three wood-engraved text illustrations. Covers soiled and somewhat worn, scattered foxing throughout, front cover neatly reattached. Early signatures of J.H. and J.W. Jerome on endpapers in ink.
A classic work on digestion, this was the first accurate scientific study of the processes of the gastric system. This was facilitated, not always enthusiastically, by Alexis St. Martin, Beaumont's subject, who "had a hole blown into his stomach by the accidental discharge of a musket loaded with duck shot. The permanent gastric fistula or 'window' that this wound left in St. Martin's abdomen enabled Beaumont to make the first accurate scientific study of the physiological processes of gastric digestion ... His researches established the presence and role of hydrochloric acid in the stomach, the temperature of the stomach during digestion, the movement of the stomach walls, and the relative digestibility of certain foods, all findings that revolutionized current theories of the physiology of digestion" --(Grolier Medicine). Dibner, Heralds of Science 130, Garrison-Morton 989, Grolier American 38; Grolier/Horblit 10; Grolier Medicine 61; Heirs of Hippocrates 1141; Osler 1972; Norman 152; Streeter 4155.

C The Estate of Herman Steinberg

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